All were included as riding contributions with isotropic displacement parameters 1.2 - 1.5 times those of the attached. H-atoms attached to carbon were placed in calculated positions (C-H = 0.95 - 0.98 Å). Colourless plate-like crystals for X-ray diffraction were obtained by further crystallization of the product from acetic acid. After cooling the mixture was poured into cold water (50 ml) and the precipitate was filtered off, washed with water, dried under vacuum and crystallized from dioxane-water (3:1vv) to afford the product in 85% yield. A mixture of 2.01 g (0.01 mol) 5-amino-3-methyl-1-phenyl-1 H -pyrazole-4-carbaldehyde and 1.32 g (0.01 mol) of 2,5-di- methoxytetrahydrofuran in acetic acid (15 ml) was heated under reflux for 2 h. O1 interactions across centers of symmetry form dimers which are further associated into corrugated sheets running approximately parallel to (100) via weak C15- H15.This hidden gem is a beautifully updated 4BR/3BA 2 story home with an additi. 1), the central pyrazole ring makes dihedral angles of 58.99 (5) and 34.95 (5)°, respectively, with the the pyrrolyl and phenyl rings. for sale: 1998 Edgeview DR, San Jose, CA 95122. Based on these findings and as part of our on-going study of the synthesis of bio-heterocyclic molecules, we report in this study the crystal structure of the title compound. In addition the title compound and its analogs have proved to be versatile compounds for use in the synthesis of several heterocycles (Farghaly & El-Kashef, 2005).
Moreover, pyrazolopyrazines are also used as fluorescent and disperse dyes in dye chemistry (Rangnekar & Dhamnaskar, 1990 Kopp et al. , 2005) and anti-inflammatory (Udupi et al.
, 1996), anti-tumor (Taylor & Patel, 1992), anticonvulsant (Ozdemir et al. and substituted pyrazolines exhibit a variety of biological activities displaying anti-bacterial (Nauduri & Reddy, 1998), anti-fungal (Korgaokar et al.
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